Intravitreal aflibercept for proliferative diabetic retinopathy

Intravitreal injection of pegaptanib sodium for proliferative diabetic retinopathy.

BACKGROUND To compare the efficacy of intravitreal pegaptanib (IVP) with panretinal laser photocoagulation (PRP) in the treatment of active proliferative diabetic retinopathy (PDR). METHODS A prospective, randomised, controlled, open-label, exploratory study. Twenty subjects with active PDR were randomly assigned at a 1:1 ratio to receive treatment in one eye either with IVP (0.3 mg) every 6 ...

Intravitreal Bevacizumab in the Surgical Treatment of Proliferative Diabetic Retinopathy

T R E ATM E N T O F PD R In 2005, after our initial encouraging experience with intravitreal bevacizumab for age-related macular degeneration, I began to use it in patients with rubeosis. The first patient I treated presented with bilateral neovascularization, rubeosis in the right eye, and partial vitreous hemorrhage in the left eye.1 I applied panretinal photocoagulation (PRP) for the left ey...

Proliferative diabetic retinopathy.

Role of Adjunctive Use of Intravitreal Bevacizumab for Severe Proliferative Diabetic Retinopathy before Vitrectomy

Purpose: To evaluate the safety and efficacy of intravitreal injection of bevacizumab advanced to vitrectomy for severe proliferative diabetic retinopathy. Methods: This is a prospective study in which, Ten eyes of ten patients with an average age 54.1 ±6.5 years (45-64 years old) complaining of severe proliferative diabetic retinopathy were investigated. An intravitreal injection of 1.25mg bev...

Macular Edema Formation and Deterioration of Retinal Function after Intravitreal Bevacizumab Injection for Proliferative Diabetic Retinopathy

PURPOSE To report a case of proliferative diabetic retinopathy (PDR) showing transient macular edema (ME) and deteriorated retinal function after intravitreal bevacizumab injection (IVB). METHODS AND RESULTS A 53-year-old man received IVB (1.25 mg/0.05 ml) in both eyes for the treatment of PDR. There was no treatment-related complication. However, he complained of photopsia in both eyes 6 h a...